PDB ID: 5NT4
Hetero Atom Contents
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Structure summary
Code : | 5NT4 PDBj RCSB PDB PDBe | ||||||||||||||||||||||||
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Header : | HYDROLASE | ||||||||||||||||||||||||
Title : | Crystal structure of TNKS2 in complex with 2-[4-(morpholin-4-yl)phenyl]-3,4-dihydroquinazolin-4-one | ||||||||||||||||||||||||
Release Data : | 2018-03-07 | ||||||||||||||||||||||||
Compound : |
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Source : |
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Authors : | Nkizinkiko, Y., Haikarainen, T., Lehtio, L. | ||||||||||||||||||||||||
Keywords : | Tankyrase, Inhibitor, ARTD6, PARP5b, hydrolase | ||||||||||||||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 1.90 Å ) | ||||||||||||||||||||||||
Citation : |
2-Phenylquinazolinones as dual-activity tankyrase-kinase inhibitors.
Nkizinkiko, Y.,Desantis, J.,Koivunen, J.
et al.
PubMed: 29374194 |
Reaction
Chain : | H, I | ||||||||||||||||
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UniProt : | Q9H2K2 (TNKS2_HUMAN) | ||||||||||||||||
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