PDB ID: 5NPP
Hetero Atom Contents
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Code | Name | Style | Show | Link | |
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6EJ | (1r)-1-[(4-{[(6,7-dihydro[1,4]dioxino[2,3-C]pyridazin-3-yl)methyl]amino}piperidin-1-yl)methyl]-9-fluoro-1,2-dihydro-4h-pyrrolo[3,2,1-ij]quinolin-4-one | PoSSuM | |||
94K | ~{N}-[(1~{R})-2-azanyl-1-phenyl-ethyl]-5-(2-chlorophenyl)-2-methyl-thiophene-3-carboxamide | PoSSuM | |||
DMS | Dimethyl sulfoxide | PoSSuM | |||
GOL | Glycerol | PoSSuM | |||
MN | Manganese (II) ion | PoSSuM | |||
NA | Sodium ion | PoSSuM |
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Download interaction data: 5NPP
Structure summary
Code : | 5NPP PDBj RCSB PDB PDBe | ||||||||||||||||||||||||||||||||||||
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Header : | ISOMERASE | ||||||||||||||||||||||||||||||||||||
Title : | 2.22A STRUCTURE OF THIOPHENE2 AND GSK945237 WITH S.AUREUS DNA GYRASE AND DNA | ||||||||||||||||||||||||||||||||||||
Release Data : | 2017-07-12 | ||||||||||||||||||||||||||||||||||||
Compound : |
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Source : |
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Authors : | Bax, B.D., Chan, P.F., Stavenger, R.A. | ||||||||||||||||||||||||||||||||||||
Keywords : | TYPE IIA TOPOISOMERASE, ANTIBACTERIAL, INHIBITOR, ISOMERASE | ||||||||||||||||||||||||||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.2200 Å ) | ||||||||||||||||||||||||||||||||||||
Citation : |
Thiophene antibacterials that allosterically stabilize DNA-cleavage complexes with DNA gyrase.
Chan, P.F.,Germe, T.,Bax, B.D.
et al.
PubMed: 28507124 |
Reaction
Chain : | B, D | ||||||||
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UniProt : | P66937 (GYRB_STAAN) | ||||||||
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Chain : | B, D | ||||||||
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UniProt : | Q99XG5 (GYRA_STAAN) | ||||||||
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