Brand  (β version)

PDB ID: 5NPF

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Ligands
Code Name Style Show Link
945 [(1~{R},2~{R},3~{R},4~{S},5~{R})-2-(hydroxymethyl)-3,4,5,6-tetrakis(oxidanyl)cyclohexyl] hydrogen sulfate PoSSuM
CA Calcium ion PoSSuM
EDO 1,2-ethanediol PoSSuM
Non-standard Residues
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Glycosylation
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Structure summary

Code : 5NPF   PDBj   RCSB PDB   PDBe
Header : HYDROLASE
Title : Crystal structure of txGH116 (beta-glucosidase from Thermoanaerobacterium xylolyticum) in complex with beta Cyclophellitol Cyclosulfate probe ME594
Release Data : 2017-08-09
Compound :
mol_id molecule chains synonym
1 Glucosylceramidase A txGH116
ec: 3.2.1.45
Source :
mol_id organism_scientific expression_system
1 Thermoanaerobacterium xylanolyticum  (taxid:29329) Escherichia coli  (taxid:562)
gene: Thexy_2211
Authors : Wu, L., Offen, W.A., Breen, I.Z., Davies, G.J.
Keywords : HYDROLASE
Exp. method : X-RAY DIFFRACTION ( 1.38 Å )
Citation :

1,6-Cyclophellitol Cyclosulfates: A New Class of Irreversible Glycosidase Inhibitor.

Artola, M.,Wu, L.,Ferraz, M.J.  et al.
(2017)  ACS Cent Sci  3 : 784 - 793

PubMed: 28776021
DOI: 10.1021/acscentsci.7b00214

Reaction

Chain : A
UniProt : F6BL85 (F6BL85_THEXL)
Reaction : -