Het-PDB Navi2 (PDB: 5N10)

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Ligands
Code	Name		Style	Show	Link
C8L	Cucurbit[8]uril				PoSSuM
GOL	Glycerol				PoSSuM

Non-standard Residues
Code	Name	Show
TPO	Phosphothreonine

Glycosylation
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Download interaction data: 5N10

Code :

5N10 PDBj RCSB PDB PDBe

Header :

TRANSCRIPTION

Title :

Cucurbit[8]uril and 14-3-3 based binary bivalent supramolecular-protein assembly platform

Release Data :

2017-05-24

Compound :

mol_id	molecule	chains	synonym
1	Estrogen receptor	F,C,D	ER,ER-alpha,Estradiol receptor,Nuclear receptor subfamily 3 group A member 1
	fragment: UNP residues 584-595 mutation: T593TPO other_details: peptide derived from Estrogen receptor alpha modified with a FGG tag

mol_id	molecule	chains	synonym
2	14-3-3 protein beta/alpha	A	Protein 1054,Protein kinase C inhibitor protein 1,KCIP-1

mol_id	molecule	chains	synonym
3	14-3-3 protein beta/alpha	B	Protein 1054,Protein kinase C inhibitor protein 1,KCIP-1
	other_details: MTMDKSELVQ KAKLAEQAER YDDMAAAMKA VTEQGHELSN EERNLLSVAY KNVVGARRSS WRVISSIEQK TERNEKKQQM GKEYREKIEA ELQDICNDVL ELLDKYLIPN ATQPESKVFY LKMKGDYFRY LSEVASGDNK QTTVSNSQQA YQEAFEISKK EMQPTHPIRL GLALNFSVFY YEILNSPEKA CSLAKTAFDE AIAELDTLNE ESYKDSTLIM QLLRDNLTLW TSENQGDEGD AGEGEN

Source :

mol_id	organism_scientific	organism_common
1	Homo sapiens (taxid:9606)	Human
	synthetic: yes

mol_id	organism_scientific	organism_common	expression_system
2	Homo sapiens (taxid:9606)	Human	Escherichia coli BL21(DE3) (taxid:469008)
	gene: YWHAB

mol_id	organism_scientific	organism_common	expression_system
3	Homo sapiens (taxid:9606)	Human	Escherichia coli BL21(DE3) (taxid:469008)
	gene: YWHAB

Authors :

de Vink, P.J., Ottmann, C.

Keywords :

supramolecular complex, scaffold protein, host-guest, transcription

Exp. method :

X-RAY DIFFRACTION ( 1.600 Å )

Citation :

A Binary Bivalent Supramolecular Assembly Platform Based on Cucurbit[8]uril and Dimeric Adapter Protein 14-3-3.

de Vink, P.J.,Briels, J.M.,Schrader, T. et al.
(2017) Angew. Chem. Int. Ed. Engl. 56 : 8998 - 9002

PDB ID: 5N10