Het-PDB Navi2 (PDB: 5MXO)

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Ligands
Code	Name	Link
CL	Chloride ion	PoSSuM
FSC	Fusicoccin	PoSSuM
MG	Magnesium ion	PoSSuM

Non-standard Residues
Code	Name	Show
TPO	Phosphothreonine

Glycosylation
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Download interaction data: 5MXO

Code :

5MXO PDBj RCSB PDB PDBe

Header :

ANTITUMOR PROTEIN

Title :

Crystal structure of 14-3-3sigma and a p53 C-terminal 12-mer synthetic phosphopeptide stabilized by Fusicoccin-A

Release Data :

2017-11-08

Compound :

mol_id	molecule	chains	synonym
1	14-3-3 protein sigma	A	Epithelial cell marker protein 1,Stratifin

mol_id	molecule	chains
2	p53 C-terminal 12 amino acids	P

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Homo sapiens (taxid:9606)	Human	Escherichia coli (taxid:562)
	gene: SFN, HME1

mol_id	organism_scientific
2	Synthetic construct (taxid:32630)
	synthetic: yes

Authors :

Andrei, S., Ottmann, C., Leysen, S.

Keywords :

14-3-3 p53 Fusicoccin antitumor protein, ANTITUMOR PROTEIN

Exp. method :

X-RAY DIFFRACTION ( 1.2000 Å )

Citation :

Small-molecule stabilization of the p53 - 14-3-3 protein-protein interaction.

Doveston, R.G.,Kuusk, A.,Andrei, S.A. et al.
(2017) FEBS Lett. 591 : 2449 - 2457

PDB ID: 5MXO