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Ligands
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CZA (6ar,11as,11br)-10-acetyl-9-hydroxy-7,7-dimethyl-2,6,6a,7,11a,11b-hexahydro-11h-pyrrolo[1',2':2,3]isoindolo[4,5,6-Cd]indol-11-one
K Potassium ion
MG Magnesium ion
MGF Trifluoromagnesate
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Code : 5MPM   PDBj   RCSB PDB   PDBe
Header : HYDROLASE
Title : SERCA2a from pig heart
Release Data : 2018-01-17
Compound :
mol_id molecule chains synonym
1 Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 A SR Ca(2+)-ATPase 2,Calcium pump 2,Calcium-transporting ATPase sarcoplasmic reticulum type,slow twitch skeletal muscle isoform,Endoplasmic reticulum class 1/2 Ca(2+) ATPase
ec: 3.6.3.8
Source :
mol_id organism_scientific organism_common
1 Sus scrofa  (taxid:9823) Pig
Authors : Drachmann, N.D., Sitsel, A., Andersen, J.L., Nissen, P., Olesen, C.
Keywords : Ca2+-ATPase, SERCA, hydrolase
Exp. method : X-RAY DIFFRACTION ( 3.300 Å )
Citation :

Structures of the heart specific SERCA2a Ca2+-ATPase.

Sitsel, A.,De Raeymaecker, J.,Drachmann, N.D.  et al.
(2019)  Embo J.  38

PubMed: 30777856
DOI: 10.15252/embj.2018100020

Chain : A
UniProt : P11607 (AT2A2_PIG)
Reaction: EC: Evidence:
Physiological Direction:
ATP + Ca(2+)(in) + H2O = ADP + Ca(2+)(out) + H(+) + phosphate 7.2.2.10 PubMed:30777856
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