Het-PDB Navi2 (PDB: 5MKF)

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Ligands
Code	Name	Link
CA	Calcium ion	PoSSuM
CHS	4-amino-5-cyclohexyl-3-hydroxy-pentanoic acid	PoSSuM
PLM	Palmitic acid	PoSSuM
PX6	1,2-dipalmitoyl-sn-glycero-3-phosphate	PoSSuM

Non-standard Residues
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Glycosylation
Code	Name	Emphasize
NAG	2-acetamido-2-deoxy-beta-D-glucopyranose

Modification
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Download interaction data: 5MKF

Code :

5MKF PDBj RCSB PDB PDBe

Header :

TRANSPORT PROTEIN

Title :

cryoEM Structure of Polycystin-2 in complex with calcium and lipids

Release Data :

2017-01-18

Compound :

mol_id	molecule	chains	synonym
1	Polycystin-2	A,B,C,D	Autosomal dominant polycystic kidney disease type II protein,Polycystic kidney disease 2 protein,Polycystwin,R48321,Transient receptor potential cation channel subfamily P member 2

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Homo sapiens (taxid:9606)	Human	Homo sapiens (taxid:9606)
	gene: PKD2, TRPP2 expression_system_common: Human expression_system_cell_line: HEK293

Authors :

Wilkes, M., Madej, M.G., Ziegler, C.

Keywords :

Ca2+ signaling, cryoEM, membrane protein structure, Polycystin-2, TRP channel, transport protein

Exp. method :

ELECTRON MICROSCOPY ( 4.2 Å )

Citation :

Molecular insights into lipid-assisted Ca(2+) regulation of the TRP channel Polycystin-2.

Wilkes, M.,Madej, M.G.,Kreuter, L. et al.
(2017) Nat. Struct. Mol. Biol. 24 : 123 - 130

PDB ID: 5MKF