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Ligands
Code Name Style Show Link
HEM Protoporphyrin ix containing Fe
C0R Corticosterone
Non-standard Residues
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Glycosylation
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Modification
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Code : 5L91   PDBj   RCSB PDB   PDBe
Header : OXIDOREDUCTASE
Title : The 2.2 A crystal structure of CYP109E1 from Bacillus megaterium bound with four corticosterone molecules
Release Data : 2016-10-05
Compound :
mol_id molecule chains
1 Cytochrome P450 A,B
ec: 1.14.14.-
Source :
mol_id organism_scientific expression_system
1 Bacillus megaterium (strain DSM 319)  (taxid:592022) Escherichia coli BL21(DE3)  (taxid:469008)
strain: DSM 319
gene: BMD_3874
expression_system_variant: C43
Authors : Jozwik, I.K., Thunnissen, A.M.W.H.
Keywords : Bacillus, Bacterial Proteins, Binding Sites, Catalysis, Corticosterone, Cytochrome P-450 Enzyme System, Cytochrome P450, Hydroxylation, Escherichia coli, Heme, Ligands, Molecular Structure, Oxidation-Reduction, Oxygen, Protein, Protein Structure, Secondary, Steroids, Substrate Specificity, oxidoreductase
Exp. method : X-RAY DIFFRACTION ( 2.2000 Å )
Citation :

Structural basis of steroid binding and oxidation by the cytochrome P450 CYP109E1 from Bacillus megaterium.

Jozwik, I.K.,Kiss, F.M.,Abdulmughni, A.  et al.
(2016)  Febs J.  283 : 4128 - 4148

PubMed: 27686671
DOI: 10.1111/febs.13911

Chain : A, B
UniProt : D5DKI8 (D5DKI8_PRIM3)
Reaction : -