Het-PDB Navi2 (PDB: 5L11)

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Ligands
Code	Name		Style	Show	Link
RJW	(1r,3ar,6ar)-5-hexyl-4-phenyl-3a-(1-phenylethenyl)-1,2,3,3a,6,6a-hexahydropentalen-1-ol				PoSSuM

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Download interaction data: 5L11

Code :

5L11 PDBj RCSB PDB PDBe

Header :

transcription/inhibitor

Title :

Human Liver Receptor Homologue-1 (LRH-1) Bound to RJW100 and a Fragment of TIF-2

Release Data :

2016-10-12

Compound :

mol_id	molecule	chains	synonym
1	Nuclear receptor subfamily 5 group A member 2	A	Alpha-1-fetoprotein transcription factor,B1-binding factor,hB1F,CYP7A promoter-binding factor,Hepatocytic transcription factor,Liver receptor homolog 1,LRH-1
	fragment: unp residues 299-541

mol_id	molecule	chains
2	Tif2	C
	fragment: unp residues 740-753

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Homo sapiens (taxid:9606)	Human	Enterobacteria phage L1 (taxid:268588)
	gene: NR5A2, B1F, CPF, FTF

mol_id	organism_scientific
2	Homo sapiens (taxid:9606)
	synthetic: yes

Authors :

Mays, S.G., Ortlund, E.A.

Keywords :

nuclear receptor, agonist, transcription-inhibitor complex

Exp. method :

X-RAY DIFFRACTION ( 1.8490 Å )

Citation :

Crystal Structures of the Nuclear Receptor, Liver Receptor Homolog 1, Bound to Synthetic Agonists.

Mays, S.G.,Okafor, C.D.,Whitby, R.J. et al.
(2016) J. Biol. Chem. 291 : 25281 - 25291

PDB ID: 5L11