Brand  (β version)

PDB ID: 5KLV

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Ligands
Code Name Style Show Link
6PE 1,2-dihexanoyl-sn-glycero-3-phosphoethanolamine PoSSuM
8PE (2r)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(tetradecanoyloxy)propyl octadecanoate PoSSuM
CDL Cardiolipin PoSSuM
CL Chloride ion PoSSuM
FES Fe2/s2 (inorganic) cluster PoSSuM
FNM (5s)-5-methyl-2-(methylsulfanyl)-5-phenyl-3-(phenylamino)-3,5-dihydro-4h-imidazol-4-one PoSSuM
GOL Glycerol PoSSuM
HEC Heme C PoSSuM
HEM Protoporphyrin ix containing Fe PoSSuM
PEF Di-palmitoyl-3-sn-phosphatidylethanolamine PoSSuM
PX4 1,2-dimyristoyl-sn-glycero-3-phosphocholine PoSSuM
Non-standard Residues
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Glycosylation
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Structure summary

Code : 5KLV   PDBj   RCSB PDB   PDBe
Header : OXIDOREDUCTASE
Title : Structure of bos taurus cytochrome bc1 with fenamidone inhibited
Release Data : 2016-10-12
Compound :
mol_id molecule chains synonym
1 Cytochrome b-c1 complex subunit 1, mitochondrial A Complex III subunit 1,Core protein I,Ubiquinol-cytochrome-c reductase complex core protein 1
mol_id molecule chains synonym
2 Cytochrome b-c1 complex subunit 2, mitochondrial B Complex III subunit 2,Core protein II,Ubiquinol-cytochrome-c reductase complex core protein 2
mol_id molecule chains synonym
3 Cytochrome b C Complex III subunit 3,Complex III subunit III,Cytochrome b-c1 complex subunit 3,Ubiquinol-cytochrome-c reductase complex cytochrome b subunit
mol_id molecule chains synonym
4 Cytochrome c1, heme protein, mitochondrial D Complex III subunit 4,Complex III subunit IV,Cytochrome b-c1 complex subunit 4,Ubiquinol-cytochrome-c reductase complex cytochrome c1 subunit,Cytochrome c-1
mol_id molecule chains synonym
5 Cytochrome b-c1 complex subunit Rieske, mitochondrial E Complex III subunit 5,Cytochrome b-c1 complex subunit 5,Rieske iron-sulfur protein,RISP,Ubiquinol-cytochrome c reductase iron-sulfur subunit
ec: 1.10.2.2
mol_id molecule chains synonym
6 Cytochrome b-c1 complex subunit 7 F Complex III subunit 7,Complex III subunit VII,QP-C,Ubiquinol-cytochrome c reductase complex 14 kDa protein
mol_id molecule chains synonym
7 Cytochrome b-c1 complex subunit 8 G Complex III subunit 8,Complex III subunit VIII,Ubiquinol-cytochrome c reductase complex 9.5 kDa protein,Ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C
mol_id molecule chains synonym
8 Cytochrome b-c1 complex subunit 6, mitochondrial H Complex III subunit 6,Complex III subunit VIII,Cytochrome c1 non-heme 11 kDa protein,Mitochondrial hinge protein,Ubiquinol-cytochrome c reductase complex 11 kDa protein
mol_id molecule chains synonym
9 Cytochrome b-c1 complex subunit Rieske, mitochondrial I Complex III subunit 5,Cytochrome b-c1 complex subunit 5,Rieske iron-sulfur protein,RISP,Ubiquinol-cytochrome c reductase iron-sulfur subunit
ec: 1.10.2.2
mol_id molecule chains synonym
10 Cytochrome b-c1 complex subunit 9 J Complex III subunit 9,Complex III subunit X,Cytochrome c1 non-heme 7 kDa protein,Ubiquinol-cytochrome c reductase complex 7.2 kDa protein
mol_id molecule chains synonym
11 Cytochrome b-c1 complex subunit 10 K Complex III subunit 10,Complex III subunit XI,Ubiquinol-cytochrome c reductase complex 6.4 kDa protein
Source :
mol_id organism_scientific organism_common
1 Bos taurus  (taxid:9913) Bovine
mol_id organism_scientific organism_common
2 Bos taurus  (taxid:9913) Bovine
mol_id organism_scientific organism_common
3 Bos taurus  (taxid:9913) Bovine
mol_id organism_scientific organism_common
4 Bos taurus  (taxid:9913) Bovine
mol_id organism_scientific organism_common
5 Bos taurus  (taxid:9913) Bovine
mol_id organism_scientific organism_common
6 Bos taurus  (taxid:9913) Bovine
mol_id organism_scientific organism_common
7 Bos taurus  (taxid:9913) Bovine
mol_id organism_scientific organism_common
8 Bos taurus  (taxid:9913) Bovine
mol_id organism_scientific organism_common
9 Bos taurus  (taxid:9913) Bovine
mol_id organism_scientific organism_common
10 Bos taurus  (taxid:9913) Bovine
mol_id organism_scientific organism_common
11 Bos taurus  (taxid:9913) Bovine
Authors : Xia, D., Esser, L., Zhou, F., Zhou, Y., Xiao, Y., Tang, W.K., Yu, C.A., Qin, Z.
Keywords : mitochondrial respiratory chain, cytochrome bc1 complex, fenamidone, electron transfer, OXIDOREDUCTASE
Exp. method : X-RAY DIFFRACTION ( 2.652 Å )
Citation :

Hydrogen Bonding to the Substrate Is Not Required for Rieske Iron-Sulfur Protein Docking to the Quinol Oxidation Site of Complex III.

Esser, L.,Zhou, F.,Zhou, Y.  et al.
(2016)  J.Biol.Chem.  291 : 25019 - 25031

PubMed: 27758861
DOI: 10.1074/jbc.M116.744391

Reaction

Chain : A
UniProt : P31800 (QCR1_BOVIN)
Reaction : -
Chain : B
UniProt : P23004 (QCR2_BOVIN)
Reaction : -
Chain : C
UniProt : P00157 (CYB_BOVIN)
Reaction : -
Chain : D
UniProt : P00125 (CY1_BOVIN)
Reaction: EC: Evidence:
Physiological Direction:
a quinol + 2 Fe(III)-[cytochrome c](out) = a quinone + 2 Fe(II)-[cytochrome c](out) + 2 H(+)(out) 7.1.1.8 UniProtKB:P07143
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Chain : I
UniProt : P13272 (UCRI_BOVIN)
Reaction: EC: Evidence:
Physiological Direction:
a quinol + 2 Fe(III)-[cytochrome c](out) = a quinone + 2 Fe(II)-[cytochrome c](out) + 2 H(+)(out) 7.1.1.8 UniProtKB:P08067
-
Chain : F
UniProt : P00129 (QCR7_BOVIN)
Reaction : -
Chain : G
UniProt : P13271 (QCR8_BOVIN)
Reaction : -
Chain : H
UniProt : P00126 (QCR6_BOVIN)
Reaction : -
Chain : J
UniProt : P00130 (QCR9_BOVIN)
Reaction : -
Chain : K
UniProt : P07552 (QCR10_BOVIN)
Reaction : -