PDB ID: 5K9D
Hetero Atom Contents
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Color scheme of protein:
Code | Name | Style | Show | Link | |
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ACT | Acetate ion | PoSSuM | |||
CE9 | Dodecyl nona ethylene glycol ether | PoSSuM | |||
CL | Chloride ion | PoSSuM | |||
FNR | 1-deoxy-1-(7,8-dimethyl-2,4-dioxo-3,4-dihydro-2h-benzo[G]pteridin-1-id-10(5h)-yl)-5-O-phosphonato-D-ribitol | PoSSuM | |||
GOL | Glycerol | PoSSuM | |||
ORO | Orotic acid | PoSSuM | |||
SO4 | Sulfate ion | PoSSuM |
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Download interaction data: 5K9D
Structure summary
Code : | 5K9D PDBj RCSB PDB PDBe | ||||||||||||
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Header : | OXIDOREDUCTASE | ||||||||||||
Title : | Crystal structure of human dihydroorotate dehydrogenase at 1.7 A resolution | ||||||||||||
Release Data : | 2016-10-12 | ||||||||||||
Compound : |
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Source : |
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Authors : | Lewis, T.A., Sykes, D.B., Law, J.M., Munoz, B., Scadden, D.T., Rustiguel, J.K., Nonato, M.C., Schreiber, S.L. | ||||||||||||
Keywords : | oxidoreductase, alpha/beta barrel | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 1.7000 Å ) | ||||||||||||
Citation : |
Development of ML390: A Human DHODH Inhibitor That Induces Differentiation in Acute Myeloid Leukemia.
Lewis, T.A.,Sykes, D.B.,Law, J.M.
et al.
PubMed: 27994748 |
Reaction
Chain : | A | ||||||||
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UniProt : | Q02127 (PYRD_HUMAN) | ||||||||
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