Het-PDB Navi2 (PDB: 5JLX)

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Ligands
Code	Name		Style	Show	Link
NI	Nickel (II) ion				PoSSuM

Non-standard Residues
Code	Name	Show
C7S	2'-deoxy-5'-O-thiophosphonocytidine

Glycosylation
Code	Name	Emphasize

Modification
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Download interaction data: 5JLX

Code :

5JLX PDBj RCSB PDB PDBe

Header :

Transcription Regulator/DNA

Title :

AntpHD with 15bp DNA duplex S-monothioated at Cytidine-8

Release Data :

2016-06-22

Compound :

mol_id	molecule	chains
1	Homeotic protein antennapedia	A,D
	mutation: C335S

mol_id	molecule	chains
2	DNA (5'-D(APGPAPAPAPGPCP(C7S)PAPTPTPAPGPAP*G)-3')	B,E

mol_id	molecule	chains
3	DNA (5'-D(TPCPTPCPTPAPAPTPGPGPCPTPTPTP*C)-3')	C,F

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Drosophila melanogaster (taxid:7227)	Fruit fly	Escherichia coli (taxid:562)
	gene: Antp, CG1028

mol_id	organism_scientific
2	Unidentified (taxid:32644)
	synthetic: yes

mol_id	organism_scientific
3	Unidentified (taxid:32644)
	synthetic: yes

Authors :

White, M.A., Zandarashvili, L., Iwahara, J., Nguyen, D.

Keywords :

HOMEODOMAIN, DNA-BINDING PROTEIN, COMPLEX (HOMEODOMAIN-DNA), TRANSCRIPTION-DNA COMPLEX, Transcription Regulator-DNA complex, monothiolated DNA

Exp. method :

X-RAY DIFFRACTION ( 2.748 Å )

Citation :

Stereospecific Effects of Oxygen-to-Sulfur Substitution in DNA Phosphate on Ion Pair Dynamics and Protein-DNA Affinity.

Nguyen, D.,Zandarashvili, L.,White, M.A. et al.
(2016) Chembiochem 17 : 1636 - 1642

PDB ID: 5JLX