Het-PDB Navi2 (PDB: 5JIQ)

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Ligands
Code	Name	Link
27M	Bis(2,4-dihydroxyphenyl)methanone	PoSSuM
GOL	Glycerol	PoSSuM
NA	Sodium ion	PoSSuM

Non-standard Residues
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Download interaction data: 5JIQ

Code :

5JIQ PDBj RCSB PDB PDBe

Header :

TRANSPORT PROTEIN

Title :

Crystal Structure of Human Transthyretin in Complex with 2,2',4,4'-tetrahydroxybenzophenone (BP2)

Release Data :

2016-10-05

Compound :

mol_id	molecule	chains	synonym
1	Transthyretin	A,B	ATTR,Prealbumin,TBPA

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Homo sapiens (taxid:9606)	Human	Escherichia coli (taxid:562)
	gene: TTR, PALB

Authors :

Begum, A., Zhang, J., Olofsson, A., Andersson, P., Sauer-Eriksson, A.E.

Keywords :

transport protein, thyroxine binding, 2, 2', 4, 4'-tetrahydroxybenzophenone (BP2)

Exp. method :

X-RAY DIFFRACTION ( 1.45 Å )

Citation :

Structure-Based Virtual Screening Protocol for in Silico Identification of Potential Thyroid Disrupting Chemicals Targeting Transthyretin.

Zhang, J.,Begum, A.,Brannstrom, K. et al.
(2016) Environ. Sci. Technol. 50 : 11984 - 11993

Tetrabromobisphenol A Is an Efficient Stabilizer of the Transthyretin Tetramer.

Iakovleva, I.,Begum, A.,Brannstrom, K. et al.
(2016) Plos One 11 : e0153529 - e0153529

PDB ID: 5JIQ