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Ligands
Code Name Style Show Link
HXC Hexanoyl-coenzyme a
Non-standard Residues
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Glycosylation
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Code : 5INF   PDBj   RCSB PDB   PDBe
Header : TRANSFERASE
Title : Structural basis for acyl-CoA carboxylase-mediated assembly of unusual polyketide synthase extender units incorporated into the stambomycin antibiotics
Release Data : 2016-12-28
Compound :
mol_id molecule chains synonym
1 Carboxyl transferase A,B,C,D,E,F Putative propionyl-CoA carboxylase
Source :
mol_id organism_scientific expression_system
1 Streptomyces ambofaciens ATCC 23877  (taxid:278992) Escherichia coli BL21(DE3)  (taxid:469008)
gene: SAM23877_7108, SAMR0483
expression_system_strain: BL21(DE3)
Authors : Valentic, T.R., Ray, L., Miyazawa, T., Withall, D.M., Song, L., Osada, H., Tsai, S.C., Challis, G.L.
Keywords : Polyketide, Crotonase, Extender-Unit, Acyl-CoA, TRANSFERASE
Exp. method : X-RAY DIFFRACTION ( 2.751 Å )
Citation :

A crotonyl-CoA reductase-carboxylase independent pathway for assembly of unusual alkylmalonyl-CoA polyketide synthase extender units.

Ray, L.,Valentic, T.R.,Miyazawa, T.  et al.
(2016)  Nat Commun  7 : 13609 - 13609

PubMed: 28000660
DOI: 10.1038/ncomms13609

Chain : A, B, C, D, E, F
UniProt : A0ACI9 (A0ACI9_STRA7)
Reaction : -