Het-PDB Navi2 (PDB: 5ICK)

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Ligands
Code	Name		Style	Show	Link
FEZ	(1s,2s,3z,5s,8z)-5-hydroxy-5,9-dimethyl-2-(propan-2-yl)cyclodeca-3,8-dien-1-yl 4-hydroxybenzoate				PoSSuM

Non-standard Residues
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Glycosylation
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Modification
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Download interaction data: 5ICK

Code :

5ICK PDBj RCSB PDB PDBe

Header :

TRANSCRIPTION

Title :

A unique binding model of FXR LBD with feroline

Release Data :

2017-03-08

Compound :

mol_id	molecule	chains
1	Bile acid receptor	A,B
	fragment: UNP residues 258-486

mol_id	molecule	chains
2	Nuclear receptor coactivator 2	C,D
	fragment: UNP residues 742-752

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Homo sapiens (taxid:9606)	Human	Escherichia coli (taxid:562)
	gene: NR1H4

mol_id	organism_scientific	organism_common	expression_system
2	Homo sapiens (taxid:9606)	Human	Escherichia coli (taxid:562)
	gene: NCOA2

Authors :

Lu, Y., Li, Y.

Keywords :

Complex, TRANSCRIPTION

Exp. method :

X-RAY DIFFRACTION ( 2.4700 Å )

Citation :

A Novel Class of Natural FXR Modulators with a Unique Mode of Selective Co-regulator Assembly

Zheng, W.,Lu, Y.,Lin, S. et al.
(2017) Chembiochem 18 : 721 - 725

PDB ID: 5ICK