Het-PDB Navi2 (PDB: 5HPM)

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Ligands
Code	Name		Style	Show	Link
CY3	2-amino-3-mercapto-propionamide				PoSSuM

Non-standard Residues
Code	Name	Show
SC2	N-acetyl-L-cysteine

Glycosylation
Code	Name	Emphasize
NAG	2-acetamido-2-deoxy-beta-D-glucopyranose

Modification
Code	Name	Show

Download interaction data: 5HPM

Code :

5HPM PDBj RCSB PDB PDBe

Header :

IMMUNE SYSTEM

Title :

Cetuximab Fab in complex with cyclic linked meditope

Release Data :

2016-06-15

Compound :

mol_id	molecule	chains
1	Cetuximab Fab light chain	A,C

mol_id	molecule	chains
2	Cetuximab Fab heavy chain	B,D

mol_id	molecule	chains
3	Cyclic amidated, acetylated linked meditope	E,F

Source :

mol_id	organism_scientific	organism_common	expression_system
1	MUS MUSCULUS, HOMO SAPIENS (taxid:10090, 9606)	Mouse, human	Unidentified (taxid:32644)

mol_id	organism_scientific	organism_common	expression_system
2	MUS MUSCULUS, HOMO SAPIENS (taxid:10090, 9606)	Mouse, human	Unidentified (taxid:32644)

mol_id	organism_scientific
3	Synthetic construct (taxid:32630)
	synthetic: yes

Authors :

Bzymek, K.P., Williams, J.C.

Keywords :

antibody, anti-EGFR, immune system

Exp. method :

X-RAY DIFFRACTION ( 2.670 Å )

Citation :

Cyclization strategies of meditopes: affinity and diffraction studies of meditope-Fab complexes.

Bzymek, K.P.,Ma, Y.,Avery, K.A. et al.
(2016) Acta Crystallogr F Struct Biol Commun 72 : 434 - 442

PDB ID: 5HPM