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Ligands
Code Name Style Show Link
Non-standard Residues
Code Name Show
ORN L-ornithine
SAR Sarcosine
Glycosylation
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Modification
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Code : 5HOX   PDBj   RCSB PDB   PDBe
Header : DE NOVO PROTEIN
Title : X-ray crystallographic structure of an A-beta 17_36 beta-hairpin. Synchrotron data set. (LVFFAEDCGSNKCAII(SAR)LMV).
Release Data : 2016-03-23
Compound :
mol_id molecule chains synonym
1 Amyloid beta A4 protein A,B,C,D,E,F ABPP,APPI,APP,Alzheimer disease amyloid protein,Cerebral vascular amyloid peptide,CVAP,PreA4,Protease nexin-II,PN-II
fragment: UNP residues 687-707
mutation: V24C, G29C, G33Sar
Source :
mol_id organism_scientific organism_common
1 Homo sapiens  (taxid:9606) Human
synthetic: yes
Authors : Kreutzer, A.G., Nowick, J.S., Spencer, R.K.
Keywords : amyloid, oligomer, beta-hairpin, Alzheimer's, PROTEIN FIBRIL, DE NOVO PROTEIN
Exp. method : X-RAY DIFFRACTION ( 1.900 Å )
Citation :

X-ray Crystallographic Structures of a Trimer, Dodecamer, and Annular Pore Formed by an A beta 17-36 beta-Hairpin.

Kreutzer, A.G.,Hamza, I.L.,Spencer, R.K.  et al.
(2016)  J.Am.Chem.Soc.  138 : 4634 - 4642

PubMed: 26967810
DOI: 10.1021/jacs.6b01332

Chain : A, B, C, D, E, F
UniProt : P05067 (A4_HUMAN)
Reaction : -