Het-PDB Navi2 (PDB: 5HMR)

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Ligands
Code	Name		Style	Show	Link
FAD	Flavin-adenine dinucleotide				PoSSuM
FDZ	1-(1,2,3-thiadiazol-5-yl)-3-[3-(trifluoromethoxy)phenyl]urea				PoSSuM

Non-standard Residues
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Glycosylation
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Download interaction data: 5HMR

Code :

5HMR PDBj RCSB PDB PDBe

Header :

OXIDOREDUCTASE

Title :

Crystal structure of maize cytokinin oxidase/dehydrogenase 4 (ZmCKO4) in complex with phenylurea inhibitor 3FMTDZ

Release Data :

2016-07-27

Compound :

mol_id	molecule	chains	synonym
1	Cytokinin dehydrogenase 4	A	Cytokinin oxidase/dehydrogenase ZmCKO4
	ec: 1.5.99.12 fragment: UNP residues 22-541

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Zea mays (taxid:4577)	Maize	Escherichia coli BL21(DE3) (taxid:469008)
	gene: CKX4 expression_system_variant: Star expression_system_vector_type: PLASMID expression_system_plasmid: PTYB12

Authors :

Kopecny, D., Koncitikova, R., Briozzo, P.

Keywords :

flavoenzyme, cytokinin degradation, oxidase/dehydrogenase, Rossmann fold, oxidoreductase

Exp. method :

X-RAY DIFFRACTION ( 2.00 Å )

Citation :

Novel thidiazuron-derived inhibitors of cytokinin oxidase/dehydrogenase.

Nisler, J.,Kopecny, D.,Koncitikova, R. et al.
(2016) Plant Mol.Biol. 92 : 235 - 248

Chain :

UniProt :

E3T1W8 (E3T1W8_MAIZE)

Reaction:	EC:	Evidence:
Reaction:	Physiological Direction:	Evidence:
N(6)-dimethylallyladenine + A + H2O = 3-methyl-2-butenal + adenine + AH2	1.5.99.12	ARBA:ARBA00048224
	-	ARBA:ARBA00048224
Cofactor:	Evidence:	Note:
FAD	ECO:0000256 \| ARBA:ARBA00001974	-

PDB ID: 5HMR