Brand  (β version)

PDB ID: 5HDE

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Ligands
Code Name Style Show Link
PO4 Phosphate ion PoSSuM
Non-standard Residues
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CSP S-phosphocysteine
Glycosylation
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Structure summary

Code : 5HDE   PDBj   RCSB PDB   PDBe
Header : HYDROLASE
Title : Crystal Structure of PTPN12 Catalytic Domain
Release Data : 2017-01-18
Compound :
mol_id molecule chains synonym
1 Tyrosine-protein phosphatase non-receptor type 12 A PTP-PEST,Protein-tyrosine phosphatase G1,PTPG1
ec: 3.1.3.48
fragment: UNP RESIDUES 1-301
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human ESCHERICHIA COLI  (taxid:469008)
gene: PTPN12
expression_system_strain: BL21(DE3)
expression_system_vector_type: plasmid
expression_system_plasmid: pET28a
Authors : Dong, H., Li, S., Shi, J.
Keywords : PTPN12, PTP, protein tyrosine phosphatase, dephosphorylation, HYDROLASE
Exp. method : X-RAY DIFFRACTION ( 1.62 Å )
Citation :

Crystal Structure of PTPN12 Catalytic Domain

Dong, H.,Shi, J.,Li, J.  et al.
To Be Published 

Reaction

Chain : A
UniProt : Q05209 (PTN12_HUMAN)
Reaction: EC: Evidence:
Physiological Direction:
H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate 3.1.3.48 PROSITE- ProRule:PRU10044, PubMed:27134172, PubMed:8454633
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