Brand  (β version)

color scheme of protein:

hetatm:

x
information
centroid:
interaction residue:

chain: Hide other chain(s)

Ligands
Code Name Link
919 4-[4-({[3-tert-butyl-1-(quinolin-6-yl)-1h-pyrazol-5-yl]carbamoyl}amino)-3-fluorophenoxy]-N-methylpyridine-2-carboxamide
EDO 1,2-ethanediol
Code : 5G6V
Header : TRANSFERASE
Title : Crystal structure of the PCTAIRE1 kinase in complex with inhibitor
Release Data : 2016-11-23
Compound :
mol_id molecule chains synonym
1 CYCLIN-DEPENDENT KINASE 16 A,B CDK16, CELL DIVISION PROTEIN KINASE 16, PCTAIRE-MOTIF PROTEIN KINASE 1, SERINE/THREONINE-PROTEIN KINASE PCTAIRE-1
ec: 2.7.11.22
fragment: KINASE DOMAIN, RESIDUES 163-478
mutation: YES
Source :
mol_id organism_scientific organism_common expression_system
1 HOMO SAPIENS  (taxid:9606) HUMAN ESCHERICHIA COLI  (taxid:562)
Authors : Dixon-Clarke, S.E., Galan Bartual, S., Elkins, J., Savitsky, P., Kopec, J., Mackenzie, A., Tallant, C., Heroven, C., Burgess-Brown, N., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Bullock, A.
Keywords : TRANSFERASE
Exp. method : X-RAY DIFFRACTION ( 2.20 Å )
Citation :

Structure of the Pctaire1 Kinase in Complex with Inhibitor

Dixon-Clarke, S.E.,Shehata, S.,Sakamoto, K.  et al.
To be Published 

Chain : A, B
UniProt : Q00536 (CDK16_HUMAN)
Reaction : ATP + a protein = ADP + a phosphoprotein.