Brand  (β version)

PDB ID: 5G1C

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Ligands
Code Name Style Show Link
1PE Pentaethylene glycol PoSSuM
9RB (2e)-N-hydroxy-3-{4-[(E)-(1,3,5-trimethyl-1h-pyrazol-4-yl)diazenyl]phenyl}prop-2-enamide PoSSuM
K Potassium ion PoSSuM
PEG Di(hydroxyethyl)ether PoSSuM
ZN Zinc ion PoSSuM
Non-standard Residues
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Structure summary

Code : 5G1C   PDBj   RCSB PDB   PDBe
Header : HYDROLASE
Title : Structure of HDAC like protein from Bordetella Alcaligenes bound the photoswitchable pyrazole Inhibitor CEW395
Release Data : 2016-11-23
Compound :
mol_id molecule chains synonym
1 HISTONE DEACETYLASE-LIKE AMIDOHYDROLASE A,B HDAC-LIKE AMIDOHYDROLASE, HDAH, HDAH
ec: 3.5.1.4
Source :
mol_id organism_scientific expression_system
1 ALCALIGENES  (taxid:507) ESCHERICHIA COLI  (taxid:562)
strain: FB188
expression_system_strain: XL1 BLUE
expression_system_vector_type: PLASMID
expression_system_vector: PQE70
Authors : Kraemer, A., Meyer-Almes, F.J., Yildiz, O.
Keywords : HYDROLASE, HDAH, HDAC, HDLP
Exp. method : X-RAY DIFFRACTION ( 1.81 Å )
Citation :

Toward Photopharmacological Antimicrobial Chemotherapy Using Photoswitchable Amidohydrolase Inhibitors.

Weston, C.E.,Kramer, A.,Colin, F.  et al.
(2017)  ACS Infect Dis  3 : 152 - 161

PubMed: 27756124
DOI: 10.1021/acsinfecdis.6b00148

Reaction

Chain : A, B
UniProt : Q70I53 (HDAH_ALCSD)
Reaction : -
Cofactor: Evidence: Note:
Zn(2+) ECO:0000305 | PubMed:27756124
Binds 1 zinc ion per subunit.