Brand  (β version)

PDB ID: 5FXT

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Ligands
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0LA (2s)-2-(6-chloro-9h-carbazol-2-yl)propanoic acid PoSSuM
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Glycosylation
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Structure summary

Code : 5FXT   PDBj   RCSB PDB   PDBe
Header : TRANSFERASE
Title : Crystal Structure of Helicobacter pylori beta clamp in complex with Carprofen
Release Data : 2017-08-16
Compound :
mol_id molecule chains synonym
1 DNA POLYMERASE III SUBUNIT BETA A BETA CLAMP
ec: 2.7.7.7
Source :
mol_id organism_scientific organism_common expression_system
1 HELICOBACTER PYLORI  (taxid:85962) CAMPYLOBACTER PYLORI ESCHERICHIA COLI  (taxid:511693)
strain: 26695
organ: STOMACH LINING, UPPER INTESTINAL LINING
expression_system_strain: BL21
expression_system_vector_type: PLASMID
expression_system_vector: PET28B
Authors : Pandey, P., Gourinath, S.
Keywords : TRANSFERASE, DNA CLAMP, SLIDING CLAMP
Exp. method : X-RAY DIFFRACTION ( 1.97 Å )
Citation :

Screening of E. coli beta-clamp Inhibitors Revealed that Few Inhibit Helicobacter pylori More Effectively: Structural and Functional Characterization.

Pandey, P.,Verma, V.,Dhar, S.K.  et al.
(2018)  Antibiotics (Basel)  7

PubMed: 29324718
DOI: 10.3390/antibiotics7010005

Reaction

Chain : A
UniProt : O25242 (DPO3B_HELPY)
Reaction : -