Brand  (β version)

PDB ID: 5FWA

Hetero Atom Contents

  The number of atoms exceeds 100,000.
  So, it can not be displayed here.

Select unit:

Select hetatm:   

close
information
centroid:
interaction residue:

Select chain:   Sequence  

Data format:   

Color scheme of protein:

Ligands
Code Name Style Show Link
CA Calcium ion PoSSuM
CL Chloride ion PoSSuM
EDO 1,2-ethanediol PoSSuM
J7C 9-(6-carbamimidamido-5,6-dideoxy-beta-D-ribo-hexofuranosyl)-9h-purin-6-amine PoSSuM
PG4 Tetraethylene glycol PoSSuM
Non-standard Residues
Code Name Show
Glycosylation
Code Name Emphasize
Modification
Code Name Show

Structure summary

Code : 5FWA   PDBj   RCSB PDB   PDBe
Header : TRANSFERASE
Title : Crystal Structure of Mus musculus Protein Arginine Methyltransferase 2 with CP1
Release Data : 2016-11-09
Compound :
mol_id molecule chains
1 PROTEIN ARGININE N-METHYLTRANSFERASE 2 A
ec: 2.1.1.125
mutation: YES
Source :
mol_id organism_scientific organism_common expression_system
1 MUS MUSCULUS  (taxid:10090) HOUSE MOUSE SPODOPTERA FRUGIPERDA  (taxid:7108)
expression_system_common: FALL ARMYWORM
expression_system_cell_line: Sf21
expression_system_vector_type: BACULOVIRUS
expression_system_plasmid: PDEST20
Authors : Cura, V., Troffer-Charlier, N., Marechal, N., Bonnefond, L., Cavarelli, J.
Keywords : TRANSFERASE, S-ADENOSYL-L-METHIONINE
Exp. method : X-RAY DIFFRACTION ( 1.800 Å )
Citation :

Structural studies of protein arginine methyltransferase 2 reveal its interactions with potential substrates and inhibitors.

Cura, V.,Marechal, N.,Troffer-Charlier, N.  et al.
(2017)  FEBS J.  284 : 77 - 96

PubMed: 27879050
DOI: 10.1111/febs.13953

Reaction

Chain : A
UniProt : Q3UKX1 (Q3UKX1_MOUSE)
Reaction: EC: Evidence:
Physiological Direction:
L-arginyl-[protein] + 2 S-adenosyl-L-methionine = N(omega),N(omega)-dimethyl-L-arginyl-[protein] + 2 S-adenosyl-L- homocysteine + 2 H(+) 2.1.1.319 ARBA:ARBA00049086
-