PDB ID: 5FVV
Hetero Atom Contents
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Color scheme of protein:
Code | Name | Style | Show | Link | |
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H4B | 5,6,7,8-tetrahydrobiopterin | PoSSuM | |||
H65 | 4-methyl-6-(2-(5-(1-methylpiperidin-4-yl)pyridin-3-yl)ethyl)pyridin-2-amine | PoSSuM | |||
HEM | Protoporphyrin ix containing Fe | PoSSuM | |||
ZN | Zinc ion | PoSSuM |
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Download interaction data: 5FVV
Structure summary
Code : | 5FVV PDBj RCSB PDB PDBe | ||||||||||||
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Header : | OXIDOREDUCTASE | ||||||||||||
Title : | Structure of human nNOS R354A G357D mutant heme domain in complex with 4-methyl-6-(2-(5-(1-methylpiperidin-4-yl)pyridin-3-yl)ethyl) pyridin-2-amine | ||||||||||||
Release Data : | 2016-04-20 | ||||||||||||
Compound : |
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Authors : | Li, H., Poulos, T.L. | ||||||||||||
Keywords : | OXIDOREDUCTASE, NITRIC OXIDE SYNTHASE | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.050 Å ) | ||||||||||||
Citation : |
Potent and Selective Human Neuronal Nitric Oxide Synthase Inhibition by Optimization of the 2-Aminopyridine-Based Scaffold with a Pyridine Linker.
Wang, H.,Qin, Y.,Li, H.
et al.
PubMed: 27050842 |
Reaction
Chain : | A, B | ||||||||
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UniProt : | P29475 (NOS1_HUMAN) | ||||||||
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