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Ligands
Code Name Style Show Link
FKH N-(6-amino-1-(3-methylbenzyl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-N-methylbenzenesulfonamide
MES 2-(N-morpholino)-ethanesulfonic acid
CL Chloride ion
Non-standard Residues
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Glycosylation
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Code : 5FU0   PDBj   RCSB PDB   PDBe
Header : TRANSFERASE
Title : Pseudomonas aeruginosa RmlA in complex with allosteric inhibitor
Release Data : 2017-02-22
Compound :
mol_id molecule chains
1 GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE A,B,C,D
ec: 2.7.7.24
Source :
mol_id organism_scientific expression_system
1 PSEUDOMONAS AERUGINOSA  (taxid:287) ESCHERICHIA COLI  (taxid:562)
Authors : Alphey, M.S., Tran, F., Westwood, N.J., Naismith, J.H.
Keywords : THYMIDYLYL, TRANSFERASE, ALLOSTERIC, INHIBITOR, PSEUDOMONAS
Exp. method : X-RAY DIFFRACTION ( 1.900 Å )
Citation :

Allosteric Competitive Inhibitors of the Glucose-1-Phosphate Thymidylyltransferase (Rmla) from Pseudomonas Aeruginosa.

Tran, F.,Alphey, M.S.,Westwood, N.J.  et al.
To be Published 

Chain : A, B, C, D
UniProt : Q9HU22 (Q9HU22_PSEAE)
Reaction: EC: Evidence:
Physiological Direction:
alpha-D-glucose 1-phosphate + dTTP + H(+) = diphosphate + dTDP-alpha-D-glucose 2.7.7.24 ARBA:ARBA00001095, RuleBase:RU003706
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