Brand  (β version)

PDB ID: 5FES

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Ligands
Code Name Style Show Link
9SE (2~{R},4~{R})-2-methyl-1,3-selenazolidine-2,4-dicarboxylic acid PoSSuM
CL Chloride ion PoSSuM
CPS 3-[(3-cholamidopropyl)dimethylammonio]-1-propanesulfonate PoSSuM
SAM S-adenosylmethionine PoSSuM
SF4 Iron/sulfur cluster PoSSuM
Non-standard Residues
Code Name Show
OTY 2-hydroxy-L-tyrosine
Glycosylation
Code Name Emphasize
Modification
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Structure summary

Code : 5FES   PDBj   RCSB PDB   PDBe
Header : OXIDOREDUCTASE
Title : HydE from T. maritima in complex with (2R,4R)-MeSeTDA
Release Data : 2016-04-06
Compound :
mol_id molecule chains
1 [FeFe] hydrogenase maturase subunit HydE A
ec: 1.8.-.-
Source :
mol_id organism_scientific expression_system
1 Thermotoga maritima  (taxid:2336) Escherichia coli  (taxid:562)
gene: TM_1269, THEMA_07990, Tmari_1274
Authors : Rohac, R., Amara, P., Benjdia, A., Martin, L., Ruffie, P., Favier, A., Berteau, O., Mouesca, J.M., Fontecilla-Camps, J.C., Nicolet, Y.
Keywords : Radical SAM enzyme, FeFe-hydrogenase maturase, thiazolidine, oxidoreductase
Exp. method : X-RAY DIFFRACTION ( 1.27 Å )
Citation :

Carbon-sulfur bond-forming reaction catalysed by the radical SAM enzyme HydE.

Rohac, R.,Amara, P.,Benjdia, A.  et al.
(2016)  Nat.Chem.  8 : 491 - 500

PubMed: 27102684
DOI: 10.1038/nchem.2490

Reaction

Chain : A
UniProt : Q9X0Z6 (HYDE_THEMA)
Reaction : -
Cofactor: Evidence: Note:
[4Fe-4S] cluster ECO:0000255 | PIRSR:PIRSR004762-1
ECO:0000269 | PubMed:16137685
ECO:0000269 | PubMed:18400755
ECO:0000269 | PubMed:19706452
ECO:0000269 | PubMed:23596207
Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
[2Fe-2S] cluster ECO:0000269 | PubMed:18400755
ECO:0000269 | PubMed:19706452
ECO:0000269 | PubMed:23596207
Binds 1 [2Fe-2S] cluster.