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Ligands
Code Name Style Show Link
5UG [(3~{S})-2,2-dimethyl-3-oxidanyl-4-oxidanylidene-4-[[3-oxidanylidene-3-(2-sulfanylethylamino)propyl]amino]butyl] phosphono hydrogen phosphate
COZ Coenzyme a
EDO 1,2-ethanediol
Non-standard Residues
Code Name Show
CSX S-oxy cysteine
MLY N-dimethyl-lysine
Glycosylation
Code Name Emphasize
Modification
Code Name Show
Code : 5F38   PDBj   RCSB PDB   PDBe
Header : TRANSFERASE
Title : X-ray crystal structure of a thiolase from Escherichia coli at 1.8 A resolution
Release Data : 2016-07-13
Compound :
mol_id molecule chains synonym
1 Acetyl-CoA acetyltransferase B Acetoacetyl-CoA thiolase
ec: 2.3.1.9
fragment: UNP residues 1-393
mol_id molecule chains synonym
2 Acetyl-CoA acetyltransferase A Acetoacetyl-CoA thiolase
ec: 2.3.1.9
mol_id molecule chains synonym
3 Acetyl-CoA acetyltransferase D Acetoacetyl-CoA thiolase
ec: 2.3.1.9
fragment: UNP residues 1-392
mol_id molecule chains synonym
4 Acetyl-CoA acetyltransferase C Acetoacetyl-CoA thiolase
ec: 2.3.1.9
fragment: UNP residues 1-393
Source :
mol_id organism_scientific expression_system
1 Escherichia coli K-12  (taxid:83333) Escherichia coli  (taxid:562)
strain: K12
gene: atoB, b2224, JW2218
mol_id organism_scientific expression_system
2 Escherichia coli K-12  (taxid:83333) Escherichia coli  (taxid:562)
strain: K12
gene: atoB, b2224, JW2218
mol_id organism_scientific expression_system
3 Escherichia coli K-12  (taxid:83333) Escherichia coli  (taxid:562)
strain: K12
gene: atoB, b2224, JW2218
mol_id organism_scientific expression_system
4 Escherichia coli K-12  (taxid:83333) Escherichia coli  (taxid:562)
strain: K12
gene: atoB, b2224, JW2218
Authors : Ithayaraja, M., Neelanjana, J., Wierenga, R., Savithri, H.S., Murthy, M.R.N.
Keywords : E.coli thiolase, fatty acid metabolism, degradative enzyme, active site geometry, TRANSFERASE
Exp. method : X-RAY DIFFRACTION ( 1.90 Å )
Citation :

Crystal structure of a thiolase from Escherichia coli at 1.8 angstrom resolution.

Ithayaraja, M.,Janardan, N.,Wierenga, R.K.  et al.
(2016)  Acta Crystallogr.,Sect.F  72 : 534 - 544

PubMed: 27380370
DOI: 10.1107/S2053230X16008451

Chain : C
UniProt : P76461 (ATOB_ECOLI)
Reaction: EC: Evidence:
Physiological Direction:
2 acetyl-CoA = acetoacetyl-CoA + CoA 2.3.1.9 PROSITE-ProRule:PRU10020
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