PDB ID: 5EW8
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SO4 | Sulfate ion | PoSSuM | |||
5SF | ~{N}'-(3,5-dimethoxyphenyl)-~{N}'-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]-~{N}-propan-2-yl-ethane-1,2-diamine | PoSSuM |
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Download interaction data: 5EW8
Structure summary
Code : | 5EW8 PDBj RCSB PDB PDBe | ||||||||||||
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Header : | TRANSFERASE | ||||||||||||
Title : | FIBROBLAST GROWTH FACTOR RECEPTOR 1 IN COMPLEX WITH JNJ-4275693 | ||||||||||||
Release Data : | 2016-03-30 | ||||||||||||
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Authors : | Ogg, D., Breed, J. | ||||||||||||
Keywords : | FGFR1 KINASE INHIBITOR COMPLEX, KINASE, transferase | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 1.63 Å ) | ||||||||||||
Citation : |
Landscape of activating cancer mutations in FGFR kinases and their differential responses to inhibitors in clinical use.
Patani, H.,Bunney, T.D.,Thiyagarajan, N.
et al.
PubMed: 26992226 |
Reaction
Chain : | A, B | ||||||||
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UniProt : | P11362 (FGFR1_HUMAN) | ||||||||
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