Brand  (β version)

PDB ID: 5ETD

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Ligands
Code Name Style Show Link
5RN 1-(1~{H}-indol-3-yl)ethanone PoSSuM
NO3 Nitrate ion PoSSuM
Non-standard Residues
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Structure summary

Code : 5ETD   PDBj   RCSB PDB   PDBe
Header : DNA BINDING PROTEIN
Title : Crystal structure of the human BRPF1 bromodomain in complex with SEED14
Release Data : 2016-05-25
Compound :
mol_id molecule chains synonym
1 Peregrin A Bromodomain and PHD finger-containing protein 1,Protein Br140
fragment: UNP residues 626-740
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Escherichia coli  (taxid:562)
gene: BRPF1, BR140
Authors : Zhu, J., Caflisch, A.
Keywords : Bromodomain and PHD finger-containing protein 1(BRPF1), monocytic leukemia zinc-finger (MOZ), Inhibitor, transcription, DNA binding protein
Exp. method : X-RAY DIFFRACTION ( 1.400 Å )
Citation :

Twenty Crystal Structures of Bromodomain and PHD Finger Containing Protein 1 (BRPF1)/Ligand Complexes Reveal Conserved Binding Motifs and Rare Interactions.

Zhu, J.,Caflisch, A.
(2016)  J.Med.Chem.  59 : 5555 - 5561

PubMed: 27167503
DOI: 10.1021/acs.jmedchem.6b00215

Reaction

Chain : A
UniProt : P55201 (BRPF1_HUMAN)
Reaction : -