PDB ID: 5ER2
Hetero Atom Contents
color scheme of protein:
|Header :||HYDROLASE/HYDROLASE INHIBITOR|
|Title :||High-resolution X-ray diffraction study of the complex between endothiapepsin and an oligopeptide inhibitor. the analysis of the inhibitor binding and description of the rigid body shift in the enzyme|
|Release Data :||1991-04-15|
|Authors :||Sali, A., Veerapandian, B., Cooper, J.B., Foundling, S.I., Hoover, D.J., Blundell, T.L.|
|Keywords :||ACID PROTEINASE, HYDROLASE-HYDROLASE INHIBITOR complex|
|Exp. method :||X-RAY DIFFRACTION ( 1.8 Å )|
High-resolution X-ray diffraction study of the complex between endothiapepsin and an oligopeptide inhibitor: the analysis of the inhibitor binding and description of the rigid body shift in the enzyme.
Sali, A.,Veerapandian, B.,Cooper, J.B.
The Active Site of Aspartic Proteinases
Pearl, L.,Blundell, T.
Active Site of Acid Proteinases
Blundell, T.L.,Jones, H.B.,Khan, G.
The Three-Dimensional Structure of Acid Proteinases
Blundell, T.L.,Jenkins, J.A.,Khan, G.
Four-Fold Structural Repeat in the Acid Proteases
Blundell, T.L.,Sewell, B.T.,Mclachlan, A.D.
Structural Evidence for Gene Duplication in the Evolution of Acid Proteases
Tang, J.,James, M.N.G.,Hsu, I.N.
Homology Among Acid Proteases. Comparison of Crystal Structures at 3 Angstroms Resolution of Acid Proteases from Rhizopus Chinensis and Endothia Parasitica
Subramanian, E.,Swan, I.D.A.,Liu, M.
X-Ray Analysis and Circular Dichroism of the Acid Protease from Endothia Parasitica and Chymosin
Jenkins, J.,Tickle, I.,Sewell, T.
|UniProt :||P11838 (CARP_CRYPA)|
|Reaction :||Hydrolysis of proteins with specificity similar to that of pepsin A, prefers hydrophobic residues at P1 and P1', but does not cleave 14-Ala-|-Leu-15 in the B chain of insulin or Z-Glu-Tyr. Clots milk.|