PDB ID: 5EOL
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Structure summary
Code : | 5EOL PDBj RCSB PDB PDBe | ||||||||||||
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Header : | transferase/transferase inhibitor | ||||||||||||
Title : | Crystal structure of human Pim-1 kinase in complex with a macrocyclic quinoxaline-pyrrolodihydropiperidinone inhibitor | ||||||||||||
Release Data : | 2016-05-04 | ||||||||||||
Compound : |
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Source : |
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Authors : | Mohr, C. | ||||||||||||
Keywords : | TRANSFERASE, serine/threonine protein kinase, transferase-transferase inhibitor complex | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.20 Å ) | ||||||||||||
Citation : |
Discovery and Optimization of Macrocyclic Quinoxaline-pyrrolo-dihydropiperidinones as Potent Pim-1/2 Kinase Inhibitors.
Cee, V.J.,Chavez, F.,Herberich, B.
et al.
PubMed: 27096050 |
Reaction
Chain : | A | ||||||||||||
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UniProt : | P11309 (PIM1_HUMAN) | ||||||||||||
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