Het-PDB Navi2 (PDB: 5DVP)

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Ligands
Code	Name	Link
DRW	(2s,3r,4s)-2-[(2s,3r)-3-hydroxy-1-oxobutan-2-yl]-3-methyl-4-({(3s,5s)-5-[(sulfamoylamino)methyl]pyrrolidin-3-yl}sulfanyl)-3,4-dihydro-2h-pyrrole-5-carboxylic acid	PoSSuM
SO4	Sulfate ion	PoSSuM
POA	Phosphonoacetaldehyde	PoSSuM

Non-standard Residues
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Glycosylation
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Download interaction data: 5DVP

Code :

5DVP PDBj RCSB PDB PDBe

Header :

TRANSFERASE

Title :

Crystal structure of Mycobacterium tuberculosis L,D-transpeptidase 2 with Doripenem adduct

Release Data :

2016-09-28

Compound :

mol_id	molecule	chains	synonym
1	L,D-transpeptidase 2	A,B	LDT 2,Ldt(Mt2)
	ec: 2.3.2.- fragment: residues 58-407

Source :

mol_id	organism_scientific	expression_system
1	Mycobacterium tuberculosis (taxid:83332)	ESCHERICHIA COLI (taxid:469008)
	strain: ATCC 25618 / H37Rv gene: ldtB, lppS, Rv2518c, RVBD_2518c, P425_02624 expression_system_strain: BL21 (DE3) expression_system_vector_type: PLASMID expression_system_plasmid: pET28a

Authors :

Kumar, P., Lamichhane, G.

Keywords :

Peptidoglycan synthesis enzyme, cell wall enzyme, TRANSFERASE

Exp. method :

X-RAY DIFFRACTION ( 2.18 Å )

Citation :

Non-classical transpeptidases yield insight into new antibacterials.

Kumar, P.,Kaushik, A.,Lloyd, E.P. et al.
(2017) Nat. Chem. Biol. 13 : 54 - 61

PDB ID: 5DVP