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Ligands
Code Name Style Show Link
12P Dodecaethylene glycol
ACM Acetamide
BU1 1,4-butanediol
CAU (2s)-1-(9h-carbazol-4-yloxy)-3-(isopropylamino)propan-2-ol
CLR Cholesterol
PLM Palmitic acid
SO4 Sulfate ion
BGC Beta-D-glucopyranose
GLC Alpha-D-glucopyranose
: Polysaccharide
Non-standard Residues
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Glycosylation
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Code : 5D5A   PDBj   RCSB PDB   PDBe
Header : Membrane Protein/Hydrolase
Title : In meso in situ serial X-ray crystallography structure of the Beta2-adrenergic receptor at 100 K
Release Data : 2016-01-13
Compound :
mol_id molecule chains synonym
1 Beta-2 adrenergic receptor,Endolysin,Beta-2 adrenergic receptor A Beta-2 adrenoreceptor,Beta-2 adrenoceptor,Lysis protein,Lysozyme,Muramidase,Beta-2 adrenoreceptor,Beta-2 adrenoceptor
ec: 3.2.1.17
mutation: N187E, C54T, C97A,N187E, C54T, C97A,N187E, C54T, C97A,N187E, C54T, C97A,N187E, C54T, C97A,N187E, C54T, C97A,N187E, C54T, C97A,N187E, C54T, C97A,N187E, C54T, C97A
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Spodoptera frugiperda  (taxid:7108)
gene: ADRB2, ADRB2R, B2AR
expression_system_common: Fall Armyworm
Authors : Huang, C.-Y., Olieric, V., Warshamanage, R., Liu, X., Kobilka, B., Kay Diederichs, K., Wang, M., Caffrey, M.
Keywords : MEMBRANE PROTEIN, HYDROLASE, Membrane Protein-Hydrolase complex
Exp. method : X-RAY DIFFRACTION ( 2.4826 Å )
Citation :

In meso in situ serial X-ray crystallography of soluble and membrane proteins at cryogenic temperatures.

Huang, C.Y.,Olieric, V.,Ma, P.  et al.
(2016)  Acta Crystallogr D Struct Biol  72 : 93 - 112

PubMed: 26894538
DOI: 10.1107/S2059798315021683

Chain : A
UniProt : P07550 (ADRB2_HUMAN)
Reaction : -
Chain : A
UniProt : P00720 (ENLYS_BPT4)
Reaction: EC: Evidence:
Physiological Direction:
Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. 3.2.1.17 HAMAP-Rule:MF_04110, PubMed:4865643
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