Brand  (β version)

PDB ID: 5CQH

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Ligands
Code Name Style Show Link
CL Chloride ion PoSSuM
DC 2'-deoxycytidine-5'-monophosphate PoSSuM
EDO 1,2-ethanediol PoSSuM
ZN Zinc ion PoSSuM
Non-standard Residues
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Glycosylation
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Structure summary

Code : 5CQH   PDBj   RCSB PDB   PDBe
Header : HYDROLASE
Title : Crystal Structure of the Cancer Genomic DNA Mutator APOBEC3B
Release Data : 2015-10-07
Compound :
mol_id molecule chains synonym
1 DNA dC-dU-editing enzyme APOBEC-3B A A3B,Phorbolin-1-related protein,Phorbolin-2/3
ec: 3.5.4.-
fragment: UNP Residues 187-378
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Escherichia coli  (taxid:562)
gene: APOBEC3B
Authors : Shi, K., Kurahashi, K., Aihara, H.
Keywords : APOBEC, deaminase, HYDROLASE
Exp. method : X-RAY DIFFRACTION ( 1.730 Å )
Citation :

Crystal Structure of the DNA Deaminase APOBEC3B Catalytic Domain.

Shi, K.,Carpenter, M.A.,Kurahashi, K.  et al.
(2015)  J.Biol.Chem.  290 : 28120 - 28130

PubMed: 26416889
DOI: 10.1074/jbc.M115.679951

Reaction

Chain : A
UniProt : Q9UH17 (ABC3B_HUMAN)
Reaction: EC: Evidence:
Physiological Direction:
a 2'-deoxycytidine in single-stranded DNA + H2O + H(+) = a 2'- deoxyuridine in single-stranded DNA + NH4(+) 3.5.4.38 -
-
Cofactor: Evidence: Note:
Zn(2+) - -