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Ligands
Code Name Style Show Link
ACT Acetate ion
CB4 Pinacol[[2-amino-alpha-(1-carboxy-1-methylethoxyimino)-4-thiazoleacetyl]amino]methaneboronate
NA Sodium ion
ZN Zinc ion
Non-standard Residues
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Glycosylation
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Code : 5CHM   PDBj   RCSB PDB   PDBe
Header : HYDROLASE
Title : CRYSTAL STRUCTURE OF Fox-4 cephamycinase complexed with ceftazidime BATSI (LP06)
Release Data : 2016-08-03
Compound :
mol_id molecule chains
1 Beta-lactamase A
ec: 3.5.2.6
fragment: UNP residues 24-382
Source :
mol_id organism_scientific expression_system
1 Escherichia coli  (taxid:562) Escherichia coli  (taxid:469008)
gene: fox-4
expression_system_strain: BL21(DE3)
expression_system_vector_type: plasmid
expression_system_plasmid: pHMTEV
Authors : Malashkevich, V.N., Toro, R., Lefurgy, S., Almo, S.C.
Keywords : beta-lactamase, HYDROLASE
Exp. method : X-RAY DIFFRACTION ( 1.9 Å )
Citation :

Structures of FOX-4 Cephamycinase in Complex with Transition-State Analog Inhibitors.

Lefurgy, S.T.,Caselli, E.,Taracila, M.A.  et al.
(2020)  Biomolecules  10

PubMed: 32349291
DOI: 10.3390/biom10050671

Chain : A
UniProt : Q9L387 (Q9L387_ECOLX)
Reaction: EC: Evidence:
Physiological Direction:
a beta-lactam + H2O = a substituted beta-amino acid 3.5.2.6 RuleBase:RU361140
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