PDB ID: 5AQO
Hetero Atom Contents
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Color scheme of protein:
Code | Name | Style | Show | Link | |
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GOL | Glycerol | PoSSuM | |||
CWS | 6-methylquinazolin-4-amine | PoSSuM | |||
TRS | 2-amino-2-hydroxymethyl-propane-1,3-diol | PoSSuM | |||
DMS | Dimethyl sulfoxide | PoSSuM | |||
CL | Chloride ion | PoSSuM |
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Download interaction data: 5AQO
Structure summary
Code : | 5AQO PDBj RCSB PDB PDBe | ||||||||||||||||||||||||
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Header : | CHAPERONE | ||||||||||||||||||||||||
Title : | Fragment-based screening of HSP70 sheds light on the functional role of ATP-binding site residues | ||||||||||||||||||||||||
Release Data : | 2016-10-05 | ||||||||||||||||||||||||
Compound : |
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Source : |
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Authors : | Jones, A.M., Westwood, I.M., Osborne, J.D., Matthews, T.P., Cheeseman, M.D., Rowlands, M.G., Jeganathan, F., Burke, R., Lee, D., Kadi, N., Liu, M., Richards, M., McAndrew, C., Yahya, N., Dobson, S.E., Jones, K., Workman, P., Collins, I., van Montfort, R.L.M. | ||||||||||||||||||||||||
Keywords : | HEAT SHOCK PROTEIN, HSP70, HSP72, HSC70, ATPASE, BAG1, CHAPERONE, FRAGMENT | ||||||||||||||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.12 Å ) | ||||||||||||||||||||||||
Citation : |
A fragment-based approach applied to a highly flexible target: Insights and challenges towards the inhibition of HSP70 isoforms.
Jones, A.M.,Westwood, I.M.,Osborne, J.D.
et al.
PubMed: 27708405 |
Reaction
Chain : | A, C, E | ||||||||
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UniProt : | P11142 (HSP7C_HUMAN) | ||||||||
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Chain : | B, D, F |
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UniProt : | Q99933 (BAG1_HUMAN) |
Reaction : | - |