Brand  (β version)

color scheme of protein:

hetatm:

x
information
centroid:
interaction residue:

chain:

Ligands
Code Name Link
9XZ 3-(2-methyltetrazol-5-yl)-5-(3-thienyl)pyridin-2-amine
DMS Dimethyl sulfoxide
PEG Di(hydroxyethyl)ether
SO4 Sulfate ion
Code : 5ALT
Header : HYDROLASE
Title : ligand complex structure of soluble epoxide hydrolase
Release Data : 2015-05-13
Compound :
mol_id molecule chains synonym
1 BIFUNCTIONAL EPOXIDE HYDROLASE 2 A EPOXIDE HYDRATASE, SOLUBLE EPOXIDE HYDROLASE, SEH
ec: 3.3.2.10, 3.1.3.76
Source :
mol_id organism_scientific organism_common expression_system
1 HOMO SAPIENS  (taxid:9606) HUMAN SPODOPTERA FRUGIPERDA  (taxid:7108)
expression_system_common: FALL ARMYWORM
expression_system_cell_line: SF9
Authors : Oster, L., Tapani, S., Xue, Y., Kack, H.
Keywords : HYDROLASE
Exp. method : X-RAY DIFFRACTION ( 2.15 Å )
Citation :

Successful Generation of Structural Information for Fragment-Based Drug Discovery.

Oster, L.,Tapani, S.,Xue, Y.  et al.
(2015)  Drug Discov Today  20 : 1104

PubMed: 25931264
DOI: 10.1016/J.DRUDIS.2015.04.005

Chain : A
UniProt : P34913 (HYES_HUMAN)
Reaction : An epoxide + H(2)O = a glycol.
(9S,10S)-10-hydroxy-9- (phosphonooxy)octadecanoate + H(2)O = (9S,10S)-9,10- dihydroxyoctadecanoate + phosphate.