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Ligands
Code Name Style Show Link
AM Americium ion
4OL N,N'-butane-1,4-diylbis[1-hydroxy-N-(3-{[(1-hydroxy-6-oxo-1,6-dihydropyridin-2-yl)carbonyl]amino}propyl)-6-oxo-1,6-dihydropyridine-2-carboxamide]
GOL Glycerol
CL Chloride ion
SO4 Sulfate ion
Non-standard Residues
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Code : 4ZHG   PDBj   RCSB PDB   PDBe
Header : Metal Binding Protein/inhibitor
Title : Siderocalin-mediated recognition and cellular uptake of actinides
Release Data : 2015-08-05
Compound :
mol_id molecule chains synonym
1 Neutrophil gelatinase-associated lipocalin A,B,C,D,E,F NGAL,25 kDa alpha-2-microglobulin-related subunit of MMP-9,Lipocalin-2,Oncogene 24p3,Siderocalin LCN2,p25
fragment: residues 22-198
mutation: C87S
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Escherichia coli  (taxid:511693)
gene: LCN2, HNL, NGAL
expression_system_strain: BL21
expression_system_vector_type: plasmid
expression_system_plasmid: pGEX
Authors : Allred, B.E., Rupert, P.B., Gauny, S.S., An, D.D., Ralston, C.Y., Sturzbecher-Hoehne, M., Strong, R.K., Abergel, R.J.
Keywords : Metal Binding Protein-inhibitor complex
Exp. method : X-RAY DIFFRACTION ( 2.0500 Å )
Citation :

Siderocalin-mediated recognition, sensitization, and cellular uptake of actinides.

Allred, B.E.,Rupert, P.B.,Gauny, S.S.  et al.
(2015)  Proc.Natl.Acad.Sci.USA  112 : 10342 - 10347

PubMed: 26240330
DOI: 10.1073/pnas.1508902112

Chain : A, B, C, D, E, F
UniProt : P80188 (NGAL_HUMAN)
Reaction : -