Het-PDB Navi2 (PDB: 4Z1G)

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Ligands
Code	Name		Style	Show	Link
94M	6-chloro-9-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]-9h-purin-2-amine				PoSSuM

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Download interaction data: 4Z1G

Code :

4Z1G PDBj RCSB PDB PDBe

Header :

CHAPERONE

Title :

Crystal structure of human Trap1 with BIIB-021

Release Data :

2015-04-22

Compound :

mol_id	molecule	chains	synonym
1	Heat shock protein 75 kDa, mitochondrial	A	HSP 75,TNFR-associated protein 1,Tumor necrosis factor type 1 receptor-associated protein,TRAP-1
	fragment: UNP residues 60-561

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Homo sapiens (taxid:9606)	Human	Escherichia coli (taxid:562)
	gene: TRAP1, HSP75

Authors :

Lee, C., Park, H.K., Ryu, J.H., Kang, B.H.

Keywords :

mitochondrial Hsp90, CHAPERONE

Exp. method :

X-RAY DIFFRACTION ( 3.1 Å )

Citation :

Development of a Mitochondria-Targeted Hsp90 Inhibitor Based on the Crystal Structures of Human TRAP1

Lee, C.,Park, H.K.,Jeong, H. et al.
(2015) J.Am.Chem.Soc. 137 : 4358 - 4367

PDB ID: 4Z1G