PDB ID: 4YT1
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Structure summary
Code : | 4YT1 PDBj RCSB PDB PDBe | ||||||||||||
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Header : | TRANSCRIPTION | ||||||||||||
Title : | Human PPAR Gamma Ligand Binding Domain in complex with a Gammma Selective Synthetic Partial Agonist MEKT76 | ||||||||||||
Release Data : | 2016-03-02 | ||||||||||||
Compound : |
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Source : |
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Authors : | Oyama, T., Ohashi, M., Miyachi, H., Kusunoki, M. | ||||||||||||
Keywords : | NUCLEAR RECEPTOR, TRANSCRIPTION | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.2 Å ) | ||||||||||||
Citation : |
Peroxisome proliferator-activated receptor gamma (PPAR gamma ) has multiple binding points that accommodate ligands in various conformations: Structurally similar PPAR gamma partial agonists bind to PPAR gamma LBD in different conformations
Ohashi, M.,Gamo, K.,Oyama, T.
et al.
PubMed: 26025876 |
Reaction
Chain : | A, B |
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UniProt : | P37231 (PPARG_HUMAN) |
Reaction : | - |