PDB ID: 4XZL
Hetero Atom Contents
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Data format:
Color scheme of protein:
Code | Name | Style | Show | Link | |
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EDO | 1,2-ethanediol | PoSSuM | |||
F49 | [2,4-dioxo-3-(2,3,4,5-tetrabromo-6-methoxybenzyl)-3,4-dihydropyrimidin-1(2h)-yl]acetic acid | PoSSuM | |||
NAP | Nadp nicotinamide-adenine-dinucleotide phosphate | PoSSuM |
Code | Name | Show |
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MLY | N-dimethyl-lysine | |
MLZ | N-methyl-lysine |
Code | Name | Emphasize |
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Code | Name | Show |
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Download interaction data: 4XZL
Structure summary
Code : | 4XZL PDBj RCSB PDB PDBe | ||||||||||||
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Header : | OXIDOREDUCTASE | ||||||||||||
Title : | Crystal structure of human AKR1B10 complexed with NADP+ and JF0049 | ||||||||||||
Release Data : | 2015-11-18 | ||||||||||||
Compound : |
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Source : |
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Authors : | Cousido-Siah, A., Ruiz, F.X., Mitschler, A., Dominguez, M., de Lera, A.R., Farres, J., Pares, X., Podjarny, A. | ||||||||||||
Keywords : | TIM barrel, Aldo-keto reductase 1B10, oxidoreductase, diabetes, Halogenated compound, Cytosolic | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 1.700 Å ) | ||||||||||||
Citation : |
Structural Determinants of the Selectivity of 3-Benzyluracil-1-acetic Acids toward Human Enzymes Aldose Reductase and AKR1B10.
Ruiz, F.X.,Cousido-Siah, A.,Porte, S.
et al.
PubMed: 26549844 |
Reaction
Chain : | X | ||||||||||||||||||||||||||||||||||||||||||||||||
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UniProt : | O60218 (AK1BA_HUMAN) | ||||||||||||||||||||||||||||||||||||||||||||||||
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