Brand  (β version)

PDB ID: 4XE3

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Ligands
Code Name Style Show Link
HEM Protoporphyrin ix containing Fe PoSSuM
CL6 1-[(2-chlorophenyl)(diphenyl)methyl]-1h-imidazole PoSSuM
SO4 Sulfate ion PoSSuM
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Structure summary

Code : 4XE3   PDBj   RCSB PDB   PDBe
Header : OXIDOREDUCTASE
Title : OleP, the cytochrome P450 epoxidase from Streptomyces antibioticus involved in Oleandomycin biosynthesis: functional analysis and crystallographic structure in complex with clotrimazole.
Release Data : 2015-11-04
Compound :
mol_id molecule chains
1 Cytochrome P-450 A,B
Source :
mol_id organism_scientific expression_system
1 Streptomyces antibioticus  (taxid:1890) Escherichia coli BL21(DE3)  (taxid:469008)
gene: oleP
expression_system_vector_type: plasmid
expression_system_plasmid: pET28b
Authors : Montemiglio, L.C., Parisi, G., Scaglione, A., Savino, C., Vallone, B.
Keywords : P450, clotrimazole, epoxidase, oleandomycin, OXIDOREDUCTASE
Exp. method : X-RAY DIFFRACTION ( 2.6500 Å )
Citation :

Functional analysis and crystallographic structure of clotrimazole bound OleP, a cytochrome P450 epoxidase from Streptomyces antibioticus involved in oleandomycin biosynthesis.

Montemiglio, L.C.,Parisi, G.,Scaglione, A.  et al.
(2015)  Biochim.Biophys.Acta  1860 : 465 - 475

PubMed: 26475642
DOI: 10.1016/j.bbagen.2015.10.009

Reaction

Chain : A, B
UniProt : Q59819 (Q59819_STRAT)
Reaction : -