Het-PDB Navi2 (PDB: 4WFG)

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Ligands
Code	Name		Style	Show	Link
CA	Calcium ion				PoSSuM
TL	Thallium (I) ion				PoSSuM

Non-standard Residues
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Download interaction data: 4WFG

Code :

4WFG PDBj RCSB PDB PDBe

Header :

METAL TRANSPORT

Title :

Human TRAAK K+ channel in a Tl+ bound conductive conformation

Release Data :

2014-12-03

Compound :

mol_id	molecule	chains	synonym
1	Potassium channel subfamily K member 4	A,B	TWIK-related arachidonic acid-stimulated potassium channel protein,TRAAK,Two pore potassium channel KT4.1,Two pore K(+) channel KT4.1
	mutation: N104Q, N108Q

mol_id	molecule	chains
2	ANTI-TRAAK ANTIBODY 13E9 FAB FRAGMENT LIGHT CHAIN	D,F

mol_id	molecule	chains
3	ANTI-TRAAK ANTIBODY 13E9 FAB FRAGMENT HEAVY CHAIN	E,G

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Homo sapiens (taxid:9606)	Human	Komagataella pastoris (taxid:4922)
	gene: KCNK4, TRAAK

mol_id	organism_scientific	organism_common	expression_system
2	Mus musculus (taxid:10090)	Mouse	Mus musculus (taxid:10090)

mol_id	organism_scientific	organism_common	expression_system
3	Mus musculus (taxid:10090)	Mouse	Mus musculus (taxid:10090)

Authors :

Brohawn, S.G., MacKinnon, R.

Keywords :

Mechanosensitive ion channel, two-pore domain potassium ion channel, membrane protein, METAL TRANSPORT

Exp. method :

X-RAY DIFFRACTION ( 3.00 Å )

Citation :

Physical mechanism for gating and mechanosensitivity of the human TRAAK K+ channel.

Brohawn, S.G.,Campbell, E.B.,MacKinnon, R.
(2014) Nature 516 : 126 - 130

PDB ID: 4WFG