Het-PDB Navi2 (PDB: 4V2O)

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Ligands
Code	Name		Style	Show	Link
CLQ	N4-(7-chloro-quinolin-4-yl)-n1,n1-diethyl-pentane-1,4-diamine				PoSSuM

Non-standard Residues
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Glycosylation
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Download interaction data: 4V2O

Code :

4V2O PDBj RCSB PDB PDBe

Header :

HYDROLASE ACTIVATOR

Title :

Structure of saposin B in complex with chloroquine

Release Data :

2015-12-09

Compound :

mol_id	molecule	chains	synonym
1	SAPOSIN-B	A,B,C	CEREBROSIDE SULFATE ACTIVATOR, CSACT, DISPERSIN, SPHINGOLIPID ACTIVATOR PROTEIN 1, SAP-1, SULFATIDE/GM1 ACTIVATOR, SAPOSIN B

Source :

mol_id	organism_scientific	organism_common	expression_system
1	HOMO SAPIENS (taxid:9606)	HUMAN	ESCHERICHIA COLI (taxid:562)
	expression_system_strain: SHUFFLE EXPRESS expression_system_vector_type: PLASMID expression_system_vector: PET28A

Authors :

Zubieta, C., Lai, X., Doyle, R.P.

Keywords :

HYDROLASE ACTIVATOR, PROTEIN-LIGAND COMPLEX

Exp. method :

X-RAY DIFFRACTION ( 2.13 Å )

Citation :

The Lysosomal Protein Saposin B Binds Chloroquine.

Huta, B.P.,Mehlenbacher, M.R.,Nie, Y. et al.
(2016) Chemmedchem 11 : 277

PDB ID: 4V2O