Het-PDB Navi2 (PDB: 4UYE)

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Ligands
Code	Name		Style	Show	Link
EDO	1,2-ethanediol				PoSSuM
9F9	N-[1,3-dimethyl-2-oxo-6-(piperidin-1-yl)-2,3-dihydro-1h-benzimidazol-5-yl]-2-methoxybenzamide				PoSSuM

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Download interaction data: 4UYE

Code :

4UYE PDBj RCSB PDB PDBe

Header :

TRANSCRIPTION

Title :

BROMODOMAIN OF HUMAN BRPF1 WITH N-1,3-dimethyl-2-oxo-6-(piperidin-1- yl)-2,3-dihydro-1H-1,3-benzodiazol-5-yl-2-methoxybenzamide

Release Data :

2014-09-17

Compound :

mol_id	molecule	chains	synonym
1	PEREGRIN	A,B	BROMODOMAIN AND PHD FINGER-CONTAINING PROTEIN 1, PROTEIN BR140
	fragment: BROMODOMAIN, UNP RESIDUES 622-738

Source :

mol_id	organism_scientific	organism_common	expression_system
1	HOMO SAPIENS (taxid:9606)	HUMAN	ESCHERICHIA COLI (taxid:562)

Authors :

Chung, C., Bamborough, P., Demont, E.

Keywords :

TRANSCRIPTION, INHIBITOR, HISTONE, EPIGENETIC READER, ANTAGONIST

Exp. method :

X-RAY DIFFRACTION ( 1.65 Å )

Citation :

1,3-Dimethyl Benzimidazolones are Potent, Selective Inhibitors of the Brpf1 Bromodomain.

Demont, E.H.,Bamborough, P.,Chung, C.W. et al.
(2014) Acs Med.Chem.Lett. 5 : 1190

PDB ID: 4UYE