Brand  (β version)

color scheme of protein:

hetatm:

x
information
centroid:
interaction residue:

chain: Hide other chain(s)

Ligands
Code Name Link
09P 1-(5-ethoxypyridin-3-yl)-1,4-diazepane
NAG N-acetyl-D-glucosamine
Code : 4UM1
Header : SIGNALING PROTEIN
Title : Engineered Ls-AChBP with alpha4-alpha4 binding pocket in complex with NS3573
Release Data : 2015-07-22
Compound :
mol_id molecule chains synonym
1 ACETYLCHOLINE-BINDING PROTEIN A,B,C,D,E ACH-BINDING PROTEIN, ACHBP
mutation: YES
other_details: 1-(5-ETHOXYPYRIDIN-3-YL)-1,4-DIAZEPANE (NS3573) BINDS AT THE INTERFACE OF EACH TWO MONOMERS
Source :
mol_id organism_scientific organism_common expression_system
1 LYMNAEA STAGNALIS  (taxid:6523) GREAT POND SNAIL SPODOPTERA FRUGIPERDA  (taxid:7108)
expression_system_common: FALL ARMYWORM
expression_system_strain: SF9
expression_system_vector_type: BACULOVIRUS
expression_system_plasmid: PFASTBAC
Authors : Shahsavar, A., Kastrup, J.S., Balle, T., Gajhede, M.
Keywords : SIGNALING PROTEIN, ION CHANNEL, RECEPTOR STOICHIOMETRY, CYS-LOOP RECEPTOR, ACETYLCHOLINE BINDING PROTEIN
Exp. method : X-RAY DIFFRACTION ( 2.830 Å )
Citation :

Achbp Engineered to Mimic the Alpha4-Alpha4 Binding Pocket in Alpha4Beta2 Nicotinic Acetylcholine Receptors Reveals Interface Specific Interactions Important for Binding and Activity

Shahsavar, A.,Ahring, P.K.,Olsen, J.A.  et al.
(2015)  Mol.Pharmacol.  88 : 697

PubMed: 26180047
DOI: 10.1124/MOL.115.098061

Chain : A, B, C, D, E
UniProt : P58154 (ACHP_LYMST)
Reaction : -