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Ligands
Code Name Style Show Link
JRB 2-piperazin-1-yl-aniline
MYA Tetradecanoyl-CoA
Non-standard Residues
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Glycosylation
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Modification
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Code : 4UCN   PDBj   RCSB PDB   PDBe
Header : TRANSFERASE
Title : CRYSTAL STRUCTURE OF LEISHMANIA MAJOR N-MYRISTOYLTRANSFERASE (NMT) WITH BOUND MYRISTOYL-COA AND A FRAGMENT
Release Data : 2015-05-13
Compound :
mol_id molecule chains
1 GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE A
ec: 2.3.1.97
fragment: RESIDUES 5-421
Source :
mol_id organism_scientific expression_system
1 LEISHMANIA MAJOR  (taxid:5664) ESCHERICHIA COLI  (taxid:562)
Authors : Robinson, D.A., Wyatt, P.G.
Keywords : ACYLTRANSFERASE, TRANSFERASE, DRUG DISCOVERY, FRAGMENT
Exp. method : X-RAY DIFFRACTION ( 1.80 Å )
Citation :

Identification and Structure Solution of Fragment Hits Against Kinetoplastid N-Myristoyltransferase

Robinson, D.A.,Wyatt, P.G.
(2015)  Acta Crystallogr.,Sect.F  71 : 586

PubMed: 25945713
DOI: 10.1107/S2053230X15003040

Chain : A
UniProt : Q4Q5S8 (Q4Q5S8_LEIMA)
Reaction: EC: Evidence:
Physiological Direction:
N-terminal glycyl-[protein] + tetradecanoyl-CoA = CoA + H(+) + N-tetradecanoylglycyl-[protein] 2.3.1.97 RuleBase:RU000586
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