Het-PDB Navi2 (PDB: 4U5V)

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Ligands
Code	Name		Style	Show	Link
RH2	N~2~-{[5-(pyridin-3-yl)thiophen-2-yl]methyl}-L-lysinamide				PoSSuM

Non-standard Residues
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Glycosylation
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Download interaction data: 4U5V

Code :

4U5V PDBj RCSB PDB PDBe

Header :

TRANSPORT PROTEIN

Title :

IMPORTIN-ALPHA MINOR NLS SITE INHIBITOR

Release Data :

2015-05-13

Compound :

mol_id	molecule	chains	synonym
1	Importin subunit alpha-1	A	Importin alpha P1,Karyopherin subunit alpha-2,Pendulin,Pore targeting complex 58 kDa subunit,PTAC58,RAG cohort protein 1,SRP1-alpha
	fragment: UNP residues 72-497

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Mus musculus (taxid:10090)	Mouse	Escherichia coli (taxid:562)
	gene: Kpna2, Rch1

Authors :

Stewart, M., Valkov, E., Holvey, R.S.

Keywords :

TPX2, importin-alpha, transport protein

Exp. method :

X-RAY DIFFRACTION ( 1.9680 Å )

Citation :

Selective Targeting of the TPX2 Site of Importin-alpha Using Fragment-Based Ligand Design.

Holvey, R.S.,Valkov, E.,Neal, D. et al.
(2015) Chemmedchem 10 : 1232 - 1239

PDB ID: 4U5V