Het-PDB Navi2 (PDB: 4U5C)

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Ligands
Code	Name		Style	Show	Link
FWD	2-amino-3-(5-fluoro-2,4-dioxo-3,4-dihydro-2h-pyrimidin-1-yl)-propionic acid				PoSSuM
FWF	N,N'-[biphenyl-4,4'-diyldi(2r)propane-2,1-diyl]dipropane-2-sulfonamide				PoSSuM

Non-standard Residues
Code	Name	Show

Glycosylation
Code	Name	Emphasize
NAG	2-acetamido-2-deoxy-beta-D-glucopyranose

Modification
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Download interaction data: 4U5C

Code :

4U5C PDBj RCSB PDB PDBe

Header :

Transport protein/toxin

Title :

Crystal structure of GluA2, con-ikot-ikot snail toxin, partial agonist FW and postitive modulator (R,R)-2b complex

Release Data :

2014-08-13

Compound :

mol_id	molecule	chains	synonym
1	Glutamate receptor 2	A,B,C,D	GluR-2,AMPA-selective glutamate receptor 2,GluR-B,GluR-K2,Glutamate receptor ionotropic,AMPA 2,GluA2

mol_id	molecule	chains
2	Con-ikot-ikot	E,F

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Rattus norvegicus (taxid:10116)	Rat	Homo sapiens (taxid:9606)
	gene: Gria2, Glur2 expression_system_cell_line: HEK293S GNTI-

mol_id	organism_scientific	organism_common	expression_system
2	Conus striatus (taxid:6493)	Striated cone	Escherichia coli (taxid:562)

Authors :

Chen, L., Gouaux, E.

Keywords :

AMPA receptor, Transport protein-toxin complex

Exp. method :

X-RAY DIFFRACTION ( 3.6883 Å )

Citation :

X-ray structures of AMPA receptor-cone snail toxin complexes illuminate activation mechanism.

Chen, L.,Durr, K.L.,Gouaux, E.
(2014) Science 345 : 1021 - 1026

Chain :

A, B, C, D

UniProt :

P19491 (GRIA2_RAT)

PDB ID: 4U5C