Brand  (β version)

PDB ID: 4TSY

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Ligands
Code Name Style Show Link
HTO Heptane-1,2,3-triol PoSSuM
HXJ 2-[[(E,2s,3r)-2-(hexanoylamino)-3-oxidanyl-dec-4-enoxy]-oxidanyl-phosphoryl]oxyethyl-trimethyl-azanium PoSSuM
SO4 Sulfate ion PoSSuM
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Structure summary

Code : 4TSY   PDBj   RCSB PDB   PDBe
Header : TOXIN
Title : Crystal structure of FraC with lipids
Release Data : 2015-03-04
Compound :
mol_id molecule chains synonym
1 Fragaceatoxin C A,B,C,D fraC
Source :
mol_id organism_scientific organism_common expression_system
1 Actinia fragacea  (taxid:396334) Strawberry anemone Escherichia coli BL21(DE3)  (taxid:469008)
expression_system_vector_type: Plasmid
expression_system_plasmid: pGEM-T
Authors : Caaveiro, J.M.M., Tanaka, K., Tsumoto, K.
Keywords : Toxin, actinoporin pore-forming toxin, Membrane lipids, Phosphocholine, Lipid-protein interaction
Exp. method : X-RAY DIFFRACTION ( 3.14 Å )
Citation :

Structural basis for self-assembly of a cytolytic pore lined by protein and lipid

Tanaka, K.,Caaveiro, J.M.M.,Morante, K.  et al.
(2015)  Nat Commun  6 : 6337 - 6337

PubMed: 25716479
DOI: 10.1038/ncomms7337

Purification, cloning and characterization of fragaceatoxin C, a novel actinoporin from the sea anemone Actinia fragacea

Bellomio, A.,Morante, K.,Barlic, A.  et al.
(2009)  Toxicon  54 : 869 - 880

PubMed: 19563820
DOI: 10.1016/j.toxicon.2009.06.022

Reaction

Chain : A, B, C, D
UniProt : B9W5G6 (ACTPC_ACTFR)
Reaction : -